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Malaria

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Malaria is a vector-borne infectious disease that is widespread in tropical and subtropical regions, including parts of the Americas, Asia, and Africa. It causes disease in approximately 400 million people every year and kills between one and three million people every year, mostly young children in Sub-Saharan Africa. Malaria is commonly-associated with poverty, but is also a cause of poverty and a major hindrance to economic development.

Review Articles

25 Sep 2008

MalVac: Database of malarial vaccine candidates

Description of a new web server, intended to facilitate the identification of probable vaccine candidates, which can be freely accessed.
Source: Malaria Journal
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4 Sep 2008

Measuring maternal mortality: an overview of opportunities and options for developing countries

Difficulties with measurement must not be allowed to discourage efforts to reduce maternal mortality. Countries must be encouraged and enabled to count maternal deaths, and to act.
Source: BMC Medicine
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News

18 Nov 2008

Massive malaria vaccine trial to begin within weeks

RTS,S vaccine will undergo clinical trials in 16,000 children in seven African countries.
Source: Associated Press
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18 Nov 2008

Global Fund makes its largest round of its grants so far

Global Fund to Fight AIDS, Tuberculosis and Malaria announces 94 new grants worth US$2.75 billion. Over half the funding will go to malaria.
Source: The Global Fund to Fight AIDS, Tuberculosis and Malaria
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Editorial Opinions

15 Oct 2008

Malaria’s watershed

A Nature editorial calls for a renewed commitment to basic research.
Source: Nature
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1 Oct 2008

Divergent Goals and Commitments in Global Malaria Intervention

There is still a major gap between the funds committed and what is actually needed.
Source: PLoS Medicine
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Research Articles

17 Nov 2008

Adaptive Copy Number Evolution in Malaria Parasites

Study shows that in P. falciparum, copy number variation may compensate for mutated and less efficient genes belonging to the same biochemical pathway.
Source: PLoS Genetics
PubMed Record External link | HTML | PDF External link

14 Nov 2008

Use of malaria rapid diagnostic test to identify Plasmodium knowlesi infection

Study shows how a panel of antibodies can be used to distinguish between seven Plasmodium species.
Source: Emerging Infectious Disease
PubMed Record External link | HTML | PDF External link

Reports

15 Oct 2008

Full Prescription; better malaria treatment for more people, MSF’s experience

A report describes MSF’s work in West Africa and argues that unnecessary deaths can be avoided with simple, affordable treatment and diagnostic tools available today.
Source: Médecins Sans Frontières
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1 Aug 2008

Assessment of the Role of Intermittent Preventive Treatment for Malaria in Infants: Letter Report

Expert group concludes that IPTi holds promise as a public health intervention.
Source: Institute of Medicine
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