Communities of practice
Leishmaniasis 
Leishmania parasites are named after W.B. Leishman, who developed one of the earliest stains of Leishmania in 1901. Widespread in 22 countries in the New World and in 66 nations in the Old World, leishmaniasis is not found in South-east Asia. Human infections are found in 16 countries in Europe, including France, Italy, Greece, Malta, Spain and Portugal. Occurring in several forms, the disease is generally recognized for its cutaneous form which causes non-fatal, disfiguring lesions, although epidemics of the potentially fatal visceral form cause thousands of deaths.
Review Articles
11 Jun 2008
Modulation of dendritic cell function by Leishmania parasites
Current data regarding the complex interactions between Leishmania parasites and dendritic cells are discussed.
Source: Journal of Immunology
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17 Jan 2008
Climate Variability And Visceral Leishmaniasis In Europe1
A three-year pan-European project entitled Climate change and adaptation strategies for human health (cCASHh), funded under the European Union thematic programme on Energy, Environment and Sustainable Development (EESD-1999), began in 2000.
Source: WHO/TDR
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News
12 Jul 2008
Tests ready to start on potential new drugs for leishmaniasis, malaria and trypanosomiasis
Canadian company and university announce collaboration on in vitro testing of drug candidates.
Source: CNN Money; Upstream BioSciences
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17 Jun 2008
Cancer drug might be key weapon against leishmaniasis
Brazilian researchers have shown the efficacy of tamoxifen against Leishmania amazonensis, one of the species that causes cutaneous leishmaniasis in South America.
Source: PLoS Neglected Tropical Diseases
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Editorial Opinions
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Research Articles
25 Jun 2008
Immunity to a salivary protein of a sand fly vector protects against the fatal outcome of visceral leishmaniasis in a hamster model
Study in hamsters offers hope for development of a leishmaniasis vaccine that protects by attacking the vector’s saliva.
Source: Proc Natl Acad Sci USA
PubMed Record 
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25 Jun 2008
Age-related alteration of arginase activity impacts on severity of leishmaniasis
Younger mice shown to be more vulnerable to infection.
Source: PLoS Neglected Tropical Diseases
PubMed Record |
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Reports
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