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24 Apr 2008

Two Doses of Azithromycin to Eliminate Trachoma in a Tanzanian Community

A report from Tanzania shows this major cause of blindness can be defeated.
Source: New England Journal of Medicine
PubMed Record External link | Read... | PDF External link

1 Apr 2008

Identification of oxadiazoles as new drug leads for the control of schistosomiasis

Encouraging results from in vitro and mice studies identify oxadiazole 2-oxides as new lead compounds for schistosomiasis chemotherapy
Source: Nature Medicine
PubMed Record External link | Read...

28 Mar 2008

Rectal artemisinins for malaria: a review of efficacy and safety from individual patient data in clinical studies

Rectal administration of artemisinin derivatives has potential for early treatment for severe malaria in remote settings where injectable antimalarial therapy may not be feasible.
Source: BMC Infectious Diseases
PubMed Record External link | Read... | PDF External link

28 Mar 2008

Building a pipeline for the drugs of the future

In a TropIKA interview, Dr Bernard Pecoul, Executive Director of the Drugs for Neglected Diseases Initiative looks forward to what can be achieved using the DNDI model.
Source: TropIKA
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10 Mar 2008

Effectiveness of single dose rifampicin in preventing leprosy in close contacts of patients with newly diagnosed leprosy: cluster randomised controlled trial

Older leprosy treatment drugs have several disadvantages for use as chemoprophylaxis. A trial of the use of a newer drug, rifampicin, found that a single dose, given to contacts of patients with newly diagnosed leprosy, is effective at preventing the development of clinical leprosy at two years.
Source: BMJ
PubMed Record External link | Read... | PDF External link

5 Mar 2008

Safety and effectiveness of first line eflornithine for Trypanosoma brucei gambiense sleeping sickness in Sudan: cohort study

Eflornithine is the only alternative to melarsoprol currently registered for the treatment of second-stage human African trypanosomiasis. A study in the Sudan shows it to have acceptable safety and effectiveness as a first-line treatment.
Source: BMJ
PubMed Record External link | Read... | PDF External link

3 Mar 2008

Kenya ‘continues to use old malaria drugs’

A study finds Kenyan health workers are still prescribing non-recommended antimalarials that cause drug resistance.
Source: Scidev.net
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25 Feb 2008

Chinese fake anti-malarial drug pipeline unveiled

An international investigation has found evidence that half of all artesunate antimalarial tablets purchased in four Southeast Asian countries are counterfeit.
Source: PLoS Medicine
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13 Feb 2008

Neglected diseases get research funding boost

The African Fellowship Programme on Neglected Tropical Diseases will fund projects for African scientists to carry out biomedical or public-health research into diseases such as schistosomiasis, the filariases and helminthiases.
Source: Scidev.net
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4 Feb 2008

Is resistance developing to river blindness drug?

The results of new research add to concerns that the parasite which causes onchocerciasis (river blindness) is developing resistance to ivermectin, the only drug used in programmes seeking to control this tropical disease.
Source: Institut de Recherche Pour le Développement
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