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24 Apr 2008

Two Doses of Azithromycin to Eliminate Trachoma in a Tanzanian Community

A report from Tanzania shows this major cause of blindness can be defeated.
Source: New England Journal of Medicine
PubMed Record External link | HTML | PDF External link

1 Apr 2008

Identification of oxadiazoles as new drug leads for the control of schistosomiasis

Encouraging results from in vitro and mice studies identify oxadiazole 2-oxides as new lead compounds for schistosomiasis chemotherapy
Source: Nature Medicine
PubMed Record External link | HTML

28 Mar 2008

Rectal artemisinins for malaria: a review of efficacy and safety from individual patient data in clinical studies

Rectal administration of artemisinin derivatives has potential for early treatment for severe malaria in remote settings where injectable antimalarial therapy may not be feasible.
Source: BMC Infectious Diseases
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28 Mar 2008

Building a pipeline for the drugs of the future

In a TropIKA interview, Dr Bernard Pecoul, Executive Director Drug of the Drugs for Neglected Diseases Initiative looks forward to what can be achieved using the DNDI model.
Source: TropIKA
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10 Mar 2008

Effectiveness of single dose rifampicin in preventing leprosy in close contacts of patients with newly diagnosed leprosy: cluster randomised controlled trial

Older leprosy treatment drugs have several disadvantages for use as chemoprophylaxis. A trial of the use of a newer drug, rifampicin, found that a single dose, given to contacts of patients with newly diagnosed leprosy, is effective at preventing the development of clinical leprosy at two years.
Source: BMJ
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5 Mar 2008

Safety and effectiveness of first line eflornithine for Trypanosoma brucei gambiense sleeping sickness in Sudan: cohort study

Eflornithine is the only alternative to melarsoprol currently registered for the treatment of second-stage human African trypanosomiasis. A study in the Sudan shows it to have acceptable safety and effectiveness as a first-line treatment.
Source: BMJ
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3 Mar 2008

Kenya ‘continues to use old malaria drugs’

A study finds Kenyan health workers are still prescribing non-recommended antimalarials that cause drug resistance.
Source: Scidev.net
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27 Feb 2008

New survey finds highest rates of drug-resistant TB to date

A major survey conducted over four years has revealed that more than half of the 81 countries included now have cases of XDR-TB, the virtually untreatable form of tuberculosis.
Source: WHO
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25 Feb 2008

Chinese fake anti-malarial drug pipeline unveiled

An international investigation has found evidence that half of all artesunate antimalarial tablets purchased in four Southeast Asian countries are counterfeit.
Source: PLoS Medicine
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13 Feb 2008

Neglected diseases get research funding boost

The African Fellowship Programme on Neglected Tropical Diseases will fund projects for African scientists to carry out biomedical or public-health research into diseases such as schistosomiasis, the filariases and helminthiases.
Source: Scidev.net
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